- 作者：J. Christiaan Keurentjes ; Marta Fiocco ; Rob G. Nelissen
- 关键词：Clinically important differences ; Health-related quality of life ; Total hip replacement ; Total knee replacement ; Short form 36
- 刊名：Journal of Clinical Epidemiology
- 出版年：January, 2014
- 年：2014
- 卷：67
- 期：1
- 页码：114-120
- 全文大小：663 K
Objectives
To determine clinically important differences (CIDs) in health-related quality of life (HRQoL) after total hip replacement (THR) or total knee replacement (TKR) surgery, using the Short Form 36 (SF-36).Study Design and Setting
SF-36 scores were collected 2聽weeks before and at 1.5-6聽years after joint replacement in 586 THR and 400 TKR patients in a multicenter cohort study. We calculated distribution-based CIDs (0.8 standard deviations of the preoperative score) for each SF-36 subscale. Responders (patients with an improvement in HRQoL聽鈮ヂ燙ID of a particular subscale) were compared with nonresponders using an external validation question: willingness to undergo surgery again.
Results
CIDs for THR/TKR were physical functioning (PF), 17.9/16.7; role-physical (RP), 31.1/33.4; bodily pain (BP), 16.8/16.2; general health, 15.5/15.7; vitality, 17.3/16.7; social functioning (SF), 22.0/19.9; role-emotional, 33.7/33.6; and mental health, 14.8/14.1. CIDs of PF, RP, BP, and SF were validated by the validation question.
Conclusion
Valid and precise CIDs are estimated of PF, RP, BP, and SF, which are relevant in HRQoL subscales for THR and TKR patients. CIDs of all other subscales should be used cautiously.