Electrochemical immunosensor for detection of topoisomerase based on graphene-gold nanocomposites
详细信息 查看全文
- 作者：Guang-Xian Zhonga ; b ; 1 ; Peng Wanga ; 1 ; Fei-Huan Fud ; Shao-Huang Wenga ; Wei Chena ; Shao-Guang Lia ; Ai-Lin Liua ; ailinliu@mail.fjmu.edu.cn" class="auth_mail ; Zhao-Yang Wub ; Xia Zhub ; Xin-Hua Lina ; xhl1963@sina.com" class="auth_mail ; Jian-Hua Linb ; jianhual@126.com" class="auth_mail ; Xing-Hua Xiac
- 关键词：Electrochemical immunosensor ; Graphene&ndash ; gold nanocomposites ; Topoisomerase
- 刊名：Talanta
- 出版年：1 July 2014
- 年：2014
- 卷：125
- 期：Complete
- 页码：439-445
- 全文大小：1206 K
文摘
- •
An electrochemical “sandwich” immunosensor was developed for detection of topoisomerase.
- •
Graphene–gold nanocomposites were prepared with one-step electrochemical co-reduction.
- •
The method could respond to topoisomerase with a detection limit of 10 pg mL−1.
- •
The immunosensor exhibited a fast response, high selectivity and sensitivity, good accuracy.