Molecular dynamics of histone H1
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- 作者：Thomas W. Flanagan ; David T. Brown ; dbrown@umc.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：Linker histone ; H1 ; Nucleosome ; Mobility ; FRAP ; Photobleaching ; Chromatin
- 刊名：Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms
- 出版年：2016
- 出版时间：March 2016
- 年：2016
- 卷：1859
- 期：3
- 页码：468-475
- 全文大小：538 K
文摘
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H1 histones bind dynamically to chromatin in living cells and exchange rapidly between nucleosomes.
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A kinetic pathway for H1 binding is presented.
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Potential mechanisms for the regulation of transcription by dynamic binding of H1 are presented.
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The evidence for linker histone chaperones is reviewed.