Substituent effects on the stereochemical outcome of the baker’s yeast-mediated biotransformation of α-hydroxy- and α-acetoxymethyl-5-phenylfuran-2-yl-ethanones

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• 作者：Lá ; szló ; Csaba Bencze ; Csaba Paizs ; Monica Ioana Toş ; a ; Florin Dan Irimie
• 刊名：Tetrahedron: Asymmetry
• 出版年：2010
• 出版时间：1 March 2010
• 年：2010
• 卷：21
• 期：3
• 页码：356-364
• 全文大小：380 K

文摘

In this Letter the baker’s yeast-mediated biotransformation of variously substituted α-hydroxy- and α-acetoxymethyl-5-phenylfuran-2-yl-ethanones is described. The stereochemical outcome of the reactions was strongly influenced by the nature of the substituents on the phenyl ring.