Microarray analysis of gene expression in olive flounder liver infected with viral haemorrhagic septicaemia virus (VHSV)
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- 作者：Hyun Kook Choa ; Julan Kima ; Ji Young Moona ; Bo-Hye Nama ; Young-Ok Kima ; Woo-Jin Kima ; Jung Youn Parka ; Cheul Min Ana ; Jaehun Cheongb ; Hee Jeong Konga ; heejkong@korea.kr" class="auth_mail" title="E-mail the corresponding author
- 关键词：Viral hemorrhagic septicemia virus ; Olive flounder ; Paralichthys olivaceus ; Microarray analysis ; Gene expression ; Immune response ; Cell cycle ; Energy metabolism
- 刊名：Fish & Shellfish Immunology
- 出版年：2016
- 出版时间：February 2016
- 年：2016
- 卷：49
- 期：Complete
- 页码：66-78
- 全文大小：1702 K
文摘
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We performed expression profiling in VHSV-infected flounder livers using a 13 K cDNA chip.
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A total of 3479 genes were regulated over two-fold after infection.
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GO analysis revealed the up-regulation of immune-related genes after infection.
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These results may be useful for the identification of VHSV infection-responsible gene in flounder.