Uptake of silica covered Quantum Dots into living cells: Long term vitality and morphology study on hyaluronic acid biomaterials
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- 作者：Michele D'Amicoa ; b ; 1 ; Calogero Fioricac ; calogero.fiorica@unipa.it" class="auth_mail" title="E-mail the corresponding author ; Fabio Salvatore Palumboc ; Valeria Militellob ; Maurizio Leoneb ; Benoit Dubertretd ; Giovanna Pitarresic ; Gaetano Giammonac
- 关键词：Fluorescence confocal microscopy ; Silica Quantum Dots ; Chondrocyte bovine cells ; Hyaluronic acid ; Labelling ; Long term cell staining
- 刊名：Materials Science & Engineering C
- 出版年：2016
- 出版时间：1 October 2016
- 年：2016
- 卷：67
- 期：Complete
- 页码：231-236
- 全文大小：917 K
文摘
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Non functionalized silica-quantum dots fluorescent nanoparticles uptake is observed.
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Morphology studies of such cells could be done by confocal fluorescence microscopy.
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Labelled chondrocytes are viable until at least 14 days.
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RGD functionalized Hyaluronic Acid hydrogels are studied as cell scaffolds.
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Chondrocyte are promptly attached on RGD-functionalized hydrogels.