Anti-parkinsonian effects of fluvoxamine maleate in maternally separated rats
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- 作者：Ernest Dallé ; Willie M.U. Daniels ; Musa V. Mabandla ; mabandlam@ukzn.ac.za" class="auth_mail" title="E-mail the corresponding author
- 关键词：Maternal separation ; Anxiety ; Fluvoxamine maleate ; 6-OHDA ; Dopamine ; Parkinson&rsquo ; s disease
- 刊名：International Journal of Developmental Neuroscience
- 出版年：2016
- 出版时间：October 2016
- 年：2016
- 卷：53
- 期：Complete
- 页码：26-34
- 全文大小：953 K
文摘
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Maternal separation causes anxiety-like symptoms.
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6-OHDA lesion of the medial forebrain bundle (MFB) causes degeneration of dopaminergic neurons.
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Fluvoxamine maleate (FM) treatment decreases DA neurons vulnerability in pre-lesion treated animals.