Report of the Inaugural Meeting of the TFOS i² = initiating innovation Series: Targeting the Unmet Need for Dry Eye Treatment

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• 作者：Wendy Chao ; PhD¹ ; Carlos Belmonte ; MD ; PhD² ; José ; M. Benitez del Castillo ; MD ; PhD³ ; Anthony J. Bron ; FRCOphth FMedSci⁴ ; Harminder S. Dua ; MD ; PhD⁵ ; Kelly K. Nichols ; OD ; MPH ; PhD⁶ ; Gary D. Novack ; PhD⁷ ; Stefan Schrader ; MD ; PhD⁸ ; Mark D. Willcox ; PhD⁹ ; James S. Wolffsohn ; OD ; PhD¹⁰ ; David A. Sullivan ; MS ; PhD¹ ; ^{david.sullivan@schepens.harvard.edu" class="auth_mail" title="E-mail the corresponding author}
• 关键词：Clinical trials ; drug development ; dry eye disease (DED) ; Dry Eye WorkShop II (DEWS II) ; i2 = initiating innovation series ; Tear Film & Ocular Surface Society
• 刊名：The Ocular Surface
• 出版年：2016
• 出版时间：April 2016
• 年：2016
• 卷：14
• 期：2
• 页码：264-316
• 全文大小：5350 K

文摘

On March 21, 2015, a meeting was held in London, United Kingdom, to address the progress in targeting the unmet need for dry eye disease (DED) treatment. The meeting, which launched the i² = initiating innovation series, was sponsored by the Tear Film & Ocular Surface Society (TFOS; www.TearFilm.org) and supported by Dompé. The TFOS i² meeting was designed to review advances in the understanding of DED since publication of the 2007 TFOS International Dry Eye WorkShop (DEWS) report, and to help launch the highly anticipated sequel, DEWS II. The meeting was structured to discuss the scope of the DED problem, to review the clinical challenges of DED, and to consider the treatment challenges of DED. This article provides a synopsis of the presentations of this TFOS i² meeting.