The parathyroid hormone-related protein is secreted during the osteogenic differentiation of human dental follicle cells and inhibits the alkaline phosphatase activity and the expression of DLX3
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- 作者：C. Klingelhö ; ffer ; A. Reck ; T. Ettl ; C. Morsczeck ; christian.morsczeck@ukr.de" class="auth_mail" title="E-mail the corresponding author
- 关键词：Parathyroid hormone-related protein ; Dental follicle cells ; Periodontal development ; Osteogenic differentiation
- 刊名：Tissue and Cell
- 出版年：2016
- 出版时间：August 2016
- 年：2016
- 卷：48
- 期：4
- 页码：334-339
- 全文大小：1009 K
文摘
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Dental follicle cells secret PTHrP during osteogenic differentiation.
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PTHrP inhibits the alkaline phosphatase activity.
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PTHrP inhibits the expression of the transcription factor DLX3.
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PTHrP regulates the differentiation independently of the hedgehog pathway.