Orexin-A facilitates emergence of the rat from isoflurane anesthesia via mediation of the basal forebrain
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- 作者：Li-Na Zhanga ; 1 ; Cen Yangb ; 1 ; Peng-Rong Ouyangb ; Zhi-Chao Zhanga ; Ming-Zi Ranb ; Li Tongb ; Hai-Long Dongb ; hldong6@hotmail.com" class="auth_mail" title="E-mail the corresponding author ; Yong Liua ; liuy5599@mail.xjtu.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Orexins ; Basal forebrain ; Isoflurane anesthesia ; Emergence time
- 刊名：Neuropeptides
- 出版年：2016
- 出版时间：August 2016
- 年：2016
- 卷：58
- 期：Complete
- 页码：7-14
- 全文大小：999 K
文摘
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Isoflurane depresses the excitability of orexinergic neurons.
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During emergence of isoflurane, the activities of orexinergic neurons were restored.
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Orexin-A plays a promotive role in emergence and this effect is partly mediated by the basal forebrain.