Our results show that the Dq curve of the background stage is smooth with a low multifractal degree (0.36) and the seismicity is nearly monofractal in the Chiayi region. During the foreshock stage, the seismicity becomes active such that not only the Dq curve exhibits greater variability especially for the steep slope of Dq curve at q = 0 but also the temporal fractal dimension changes from nearly monofractal to multifractal. In the aftershock stage, the fluctuation of Dq is large and the multifractal degree is up to 1.0. The temporal multifractal property becomes more pronounced as well. Finally, when the seismicity returns to the background stage, the Dq curve becomes smooth and nearly monofractal again. Therefore, the fluctuations in the Dq spectrum of an earthquake cluster associated with a large earthquake not only give a clear picture of the temporal alterations in the seismogenic regimes but also illustrate their variability through time for a large earthquake. In addition, the variation of the slope of Dq curve at q = 0 in the foreshocks may be used as a precursor of a large earthquake.