Radiation processing: An effective quality control tool for hygienization and extending shelf life of a herbal formulation, Amritamehari churnam

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• 作者：Suchandra Chatterjee^a ; ^{c_suchandra68@yahoo.co.in" class="auth_mail" title="E-mail the corresponding author} ; ^{suchanc@barc.gov.in" class="auth_mail" title="E-mail the corresponding author} ; Vivekanand Kumar^a ; Swati Khole^b ; Bhaskar Sanyal^a ; T.S. Murali^c ; Prasad S. Variyar^a ; ^{pvariyar@barc.gov.in" class="auth_mail" title="E-mail the corresponding author}
• 关键词：Herbal formulation ; Radiation processing ; Shelf life extension ; Quality control
• 刊名：Journal of Radiation Research and Applied Sciences
• 出版年：2016
• 出版时间：January 2016
• 年：2016
• 卷：9
• 期：1
• 页码：86-95
• 全文大小：1131 K

文摘

Amritamehari churnam (AC) is an antidiabetic polyherbal formulation constituting of four herbal medicinal plants namely Phyllanthus emblica, Salacia reticulata, Tinospora cordifolia and Curcuma longa. The feasibility of using gamma irradiation at doses between 2.5 and 10 kGy to reduce microbial load and enhance shelf life of this formulation was investigated. The irradiated and non-irradiated products were stored at room temperature (25–32 °C and 50–85% R.H., 1.5 years). Acceptability of the irradiated product was assessed based on sensory, microbial, physical and chemical attributes as well as their antioxidant status. A dose 7.5 kGy was sufficient to maintain microbial quality within acceptable limit up to 18 months of storage. No significant differences in sensory properties were observed between the non-irradiated and irradiated sample. The applied dose did not cause any significant qualitative and quantitative changes in the chemical constituents, antioxidant activities as well as physical properties when measured by EPR spectroscopy.