A possible case of Garre’s sclerosing osteomyelitis from Medieval Tuscany (11th-12th centuries)

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• 作者：Valentina Giuffra^a ; ^b ; ^{v.giuffra@med.unipi.it" class="auth_mail" title="E-mail the corresponding author} ; Angelica Vitiello^a ; ^{angelicavit@tiscali.it" class="auth_mail" title="E-mail the corresponding author} ; Sara Giusiani^a ; ^{sara.giusiani@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Davide Caramella^c ; ^{davide.caramella@med.unipi.it" class="auth_mail" title="E-mail the corresponding author} ; Gino Fornaciari^a ; ^b ; ^{gino.fornaciari@med.unipi.it" class="auth_mail" title="E-mail the corresponding author}
• 关键词：Chronic periostitis ; Tibia ; 11th&ndash ; 12th centuries
• 刊名：International Journal of Paleopathology
• 出版年：2015
• 出版时间：December 2015
• 年：2015
• 卷：11
• 期：Complete
• 页码：51-55
• 全文大小：1799 K

文摘

Archaeological excavations carried out at the castle of Monte di Croce near Florence brought to light a small cemetery complex belonging to the castle church, dated back to the 11th–12th centuries. An elite stone tomb contained the skeletal remains of a male aged 35–45 years with obvious pathology of the right tibia. The proximal metaphysis and the upper half of the diaphysis appear massively enlarged as a result of severe chronic periostitis. A transverse section illustrates complete obliteration of the medullary cavity by new spongy bone, with some large cavitations. The primary, but completely remodeled tibial shaft is still recognizable. This finding and the strong sclerotic reaction with some central cavitations rule out any form of bone tumor and indicate a chronic inflammatory disease. The morphological and radiological picture and the tibial localization suggest a diagnosis of chronic sclerosing osteomyelitis of Garré, a rare form of chronic osteomyelitis characterized by an intense periosteal reaction with little or no suppuration.