En1 directs superior olivary complex neuron positioning, survival, and expression of FoxP1
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- 作者：Stefanie C. Altieria ; 1 ; Walid Jalabib ; 1 ; Tianna Zhaoa ; Rita R. Romito-DiGiacomob ; Stephen M. Maricicha ; c ; stephen.maricich@chp.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：Hearing ; Brainstem ; Auditory ; Deafness ; Nucleogenesis
- 刊名：Developmental Biology
- 出版年：2015
- 出版时间：1 December 2015
- 年：2015
- 卷：408
- 期：1
- 页码：99-108
- 全文大小：4296 K
文摘
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En1 deletion causes death of MNTB, VNTB and subsets of LSO and LNTB neurons.
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En1 is necessary for establishing correct SOC neuron positioning in the brainstem.
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The transcription factor FoxP1 lies downstream of En1 in En1-lineal SOC neurons.