Foxp transcription factors suppress a non-pulmonary gene expression program to permit proper lung development
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- 作者：Shanru Lia ; b ; c ; Michael Morleya ; b ; c ; MinMin Lua ; b ; Su Zhoua ; b ; Kathleen Stewarta ; b ; c ; Catherine A. Frenchf ; Haley O. Tuckerg ; Simon E. Fisherh ; Edward E. Morriseya ; b ; c ; d ; e ; emorrise@mail.med.upenn.edu" class="auth_mail" title="E-mail the corresponding author
- 刊名：Developmental Biology
- 出版年：2016
- 出版时间：15 August 2016
- 年：2016
- 卷：416
- 期：2
- 页码：338-346
- 全文大小：4337 K
文摘
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Foxp1/2/4 are essential for lung development.
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Combined loss of Foxp1/2/4 leads to defective lung progenitor commitment.
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Foxp1/2/4 restrict expression of non-lung genes including Hox and Pax factors.