Acute acalculous cholecystitis during the course of primary Epstein–Barr virus infection: a new case and a review of the literature

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• 作者：Chiara Iaria ; Lucia Arena ; Giovanni Di Maio ; Maria Grazia Fracassi ; Maria Silvana Leonardi ; Ciro Famulari ; Antonio Cascio
• 关键词：Acute acalculous cholecystitis ; Gallbladder ; Epstein– ; Barr virus ; Infectious mononucleosis
• 刊名：International Journal of Infectious Diseases
• 出版年：2008
• 出版时间：July 2008
• 年：2008
• 卷：12
• 期：4
• 页码：391-395
• 全文大小：130 K

文摘

Summary

Objective

The aim of this study was to describe a case of acute acalculous cholecystitis occurring in the course of primary Epstein–Barr virus (EBV) infection.

Methods

The clinical features of the case were analyzed and compared to those of three other similar cases reported in the international literature.

Results

All cases occurred in European females with cholestatic hepatitis, presented with gallbladder wall thickening, and recovered uneventfully without the need for surgical intervention.

Conclusions

Acute acalculous cholecystitis may occur during the course of acute EBV infection, especially in patients with cholestatic hepatitis. Clinicians should be aware of the possible involvement of the gallbladder during EBV infection to avoid unnecessary invasive procedures or the overuse of antibiotics.