Aptamers, antibody scFv, and antibody Fab' fragments: An overview and comparison of three of the most versatile biosensor biorecognition elements
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- 作者：Victor Crivianu-Gaita ; Michael Thompson ; mikethom@chem.utoronto.ca" class="auth_mail" title="E-mail the corresponding author
- 关键词：Biosensors ; ScFv fragments ; Fab' fragments ; Aptamers ; Biorecognition elements
- 刊名：Biosensors and Bioelectronics
- 出版年：2016
- 出版时间：15 November 2016
- 年：2016
- 卷：85
- 期：Complete
- 页码：32-45
- 全文大小：1798 K
文摘
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scFv fragments, Fab' fragments, and aptamers are common biorecognition elements.
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scFv fragments are the most customizable due to recombinant synthesis methods.
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Fab' fragments are the cheapest and quickest to develop for biosensor use.
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Aptamers have the highest affinity for their target analytes and are most stable.