A Long Noncoding RNA Regulates Sister Chromatid Cohesion
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文摘

CONCR is a human lncRNA activated by MYC and upregulated in multiple cancer types

CONCR expression is periodic and required for cell division and survival

Inactivation of CONCR causes severe defects in sister chromatid cohesion

CONCR modulates the activity of the helicase DDX11

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