• 作者：Marí ; a Eugenia Mantrana-Bermejo^a ; ^{manbeu@gmail.com} ; Trinidad Rueda-Rueda^b ; José ; Bernabeu-Wittel^c ; Francisca Gonz&#225 ; lez-Escribano^d ; Francisco Garcí ; a-Hern&#225 ; ndez^c ; Julio S&#225 ; nchez-Rom&#225 ; n^c
• 关键词：Pars planitis ; Uveí ; tis ; HLA ; Epidemiologí ; a ; Tratamiento
• 刊名：Medicina Cl¨ªnica
• 出版年：2010
• 出版时间：10 July 2010
• 年：2010
• 卷：135
• 期：5
• 页码：205-208
• 全文大小：136 K

Background and objectives

Epidemiological studies on North American patients reported an association between HLA DR15 and pars planitis. This association has not been studied in the Spanish population. The objectives of the present study were to describe the clinical and epidemiological features of patients with pars planitis diagnosed in our hospital as well as the prevalence of multiple sclerosis and HLA class I and II.

Patients and Methods

Twenty four patients with pars planitis were identified among 226 patients with uveitis diagnosed in the Ophtahlmology Department of our center from January 1992 to October 2006. Twenty four patients and 194 healthy controls underwent HLA A, B and DR genotyping.

Results

The most frequent complication was cystic macular edema. Most patients needed many medical treatments. No statistical association was found between pars planitis and HLA.

Conclusions

Epidemiological data were consistent with previously reported studies. There appears to be no association between the occurrence of pars planitis and HLA DR 15 or other known HLA genotypes in Spanish patients. However, the small sample size could have limited the power of this study.