Expanding the neutralization scope of the EchiTAb-plus-ICP antivenom to include venoms of elapids from Southern Africa

详细信息    查看全文

• 作者：André ; s Sá ; nchez^a ; Á ; lvaro Segura^a ; Mariá ; ngela Vargas^a ; Marí ; a Herrera^a ; ^b ; Mauren Villalta^a ; Ricardo Estrada^a ; Francisco Wu^a ; Thea Litschka-Koen^c ; Michael Alfred Perry^d ; Alberto Alape-Gir&oacute ; n^a ; Guillermo Le&oacute ; n^a ; ^{guillermo.leon@ucr.ac.cr}
• 关键词：Antivenom ; African adders ; Mambas ; Cobras ; Rinkhals ; Southern Africa
• 刊名：Toxicon
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：125
• 期：Complete
• 页码：59-64
• 全文大小：266 K
• 卷排序：125

文摘

EchiTab-plus-ICP is an antivenom towards venoms of snakes from Western Africa. Venoms of elapids from Swaziland were included in the immunization mixture. The neutralization scope of the EchiTab-plus-ICP was expanded to include venoms of elapids from Southern Africa. The expanded-scope antivenom has neutralization properties similar to FAV Afrique and the SVA African antivenoms. The clinical efficacy of the new EchiTab-plus-ICP in envenomations caused by elapids from Southern Africa is pending.