Not All Created Equal: Lineage Hard-Wiring in the Production of Blood

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• 作者：Francois E. Mercier¹ ; ² ; David T. Scadden¹ ; ² ; ^{david_scadden@harvard.edu" class="auth_mail" title="E-mail the corresponding author}
• 刊名：Cell
• 出版年：2015
• 出版时间：17 December 2015
• 年：2015
• 卷：163
• 期：7
• 页码：1568-1570
• 全文大小：336 K

文摘

The multiple cell types comprising blood have been thought to emerge from progenitors with progressively narrower lineage options. New data suggest that lineage fate may be determined earlier than thought and that myeloid progenitor populations are aggregates of individual lineage-restricted cells.