A Sensor for Low Environmental Oxygen in the Mouse Main Olfactory Epithelium

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• 作者：Katherin Bleymehl¹ ; ⁵ ; Anabel Pé ; rez-Gó ; mez¹ ; ⁵ ; Masayo Omura² ; ⁵ ; Ana Moreno-Pé ; rez¹ ; David Mací ; as³ ; Zhaodai Bai² ; Randall S. Johnson³ ; ⁴ ; Trese Leinders-Zufall¹ ; Frank Zufall¹ ; ^{frank.zufall@uks.eu} ; Peter Mombaerts² ; ⁶ ; ^{peter.mombaerts@gen.mpg.de}
• 刊名：Neuron
• 出版年：2016
• 出版时间：21 December 2016
• 年：2016
• 卷：92
• 期：6
• 页码：1196-1203
• 全文大小：1936 K
• 卷排序：92

文摘

Sensing the level of oxygen in the external environment is essential for survival Low oxygen directly activates sensory neurons in the mouse main olfactory epithelium These responses require the guanylate cyclase Gucy1b2 and the cation channel Trpc2 A mouse could thus rapidly assess the oxygen level in the external environment