Cortical arousal in children and adolescents with functional neurological symptoms during the auditory oddball task

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• 作者：Kasia Kozlowska ; MBBS. ; PhD. FRANZCP^a ; ^{Kkoz6421@uni.sydney.edu.au} ; ^{Kasiak@health.gov.nsw.au} ; Dmitriy Melkonian ; PhD. DSc^b ; ¹ ; ^{dmitri@med.usyd.edu.au} ; Chris J. Spooner ; Bachelors of Engineering^c ; ² ; ^{chris.spooner@brainresource.com} ; Stephen Scher ; PhD ; JD^d ; ^e ; ^{scher02138@yahoo.com} ; Russell Meares ; MD ; FRANZCP ; FRCPsych^f ; ¹ ; ^{Russell.meares@sydney.edu.au}
• 关键词：EEG ; electroencephalogram ; ERP ; event-related potential ; GMP ; generic mass potential ; PFC ; Prefrontal cortex ; dlPFC ; Dorsolateral prefrontal cortex
• 刊名：NeuroImage: Clinical
• 出版年：2017
• 出版时间：2017
• 年：2017
• 卷：13
• 期：Complete
• 页码：228-236
• 全文大小：611 K
• 卷排序：13

文摘

ERPs are used for spatiotemporal analysis of brain activation during processing following presentation of a novel stimulus. Increased ERP amplitudes in children/adolescents with functional neurological symptoms suggest increased cortical arousal. Increased cortical arousal may be a precondition for generating functional neurological symptoms. Interventions that target arousal early in the illness may improve remission and prevention chronic functional impairment.