N-acetylcysteine attenuates nicotine-induced kindling in female periadolescent rats
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- 作者：Adriana Mary Nunes Costa Okamura ; Patrí ; cia Xavier L. Gomes ; Gersilene V. de Oliveira ; Fernanda Yvelize R. de Araú ; jo ; Viviane S. Tomaz ; Adriano José ; Maia Chaves Filho ; Francisca Clé ; a F. de Sousa ; Silvâ ; nia Maria Mendes Vasconcelos ; David Freitas de Lucena ; Danielle Macê ; do ; daniellesilmacedo@gmail.com" class="auth_mail" title="E-mail the corresponding author ; danielle.macedo@ufc.br" class="auth_mail" title="E-mail the corresponding author
- 关键词：Nicotine ; Kindling ; Nicotine kindling ; Female rats ; N-acetyl cysteine ; Seizure
- 刊名：Progress in Neuropsychopharmacology & Biological Psychiatry
- 出版年：2016
- 出版时间：3 June 2016
- 年：2016
- 卷：67
- 期：Complete
- 页码：58-65
- 全文大小：930 K
文摘
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Female periadolescent rats are more vulnerable to nicotine (NIC) kindling.
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N-acetyl cysteine (NAC) attenuates the development of nicotine (NIC)-induced kindling.
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NAC prevented the decreases in GSH and increases in lipid peroxidation induced by NIC.