This study evaluated the utility of OFDI in the assessment of calcified plaques.
OFDI showed a good correlation with histology in the measurement of calcification thickness, however outer border of calcification was vague when lipid components were involved in the calcification.
Calcified nodules exhibited an atypical appearance in OFDI showing attenuation with an irregular surface.
OFDI demonstrated a greater ability to quantify and qualify coronary arterial calcification compared with IVUS.