The expression and post-transcriptional regulation of FSTL1 transcripts in placental trophoblasts
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- 作者：Jean-Francois Mouilleta ; b ; Takuya Mishimaa ; b ; Andrea Mollica do Amarante Paffaroa ; e ; Tony W. Parksa ; d ; Judy A. Zieglera ; Tianjiao Chua ; b ; Yoel Sadovskya ; b ; c ; ysadovsky@mwri.magee.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：Trophoblasts ; Hypoxia ; FSTL1 ; miR-198
- 刊名：Placenta
- 出版年：2015
- 出版时间：November 2015
- 年：2015
- 卷：36
- 期：11
- 页码：1231-1238
- 全文大小：1828 K
文摘
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FSTL1 is expressed in the human placenta, mainly in extravillous trophoblasts.
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Basal FSTL1 protein expression is low in villous trophoblasts, but is increased in hypoxic conditions.
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FSTL1 expression in trophoblasts is regulated by post-transcriptional mechanisms.
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There is no evidence of expression of the miR-198 passenger miRNA in trophoblasts, or for its effect on FSTL1 expression.