Potential role of differentially expressed lncRNAs in the pathogenesis of oral squamous cell carcinoma
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- 作者：Shanchuan Zhang ; MDa ; Lili Tian ; MDa ; Penghua Ma ; MDa ; Qiang Sun ; MDa ; Kai Zhang ; MDa ; GuanchaoWang ; MDa ; Hongchen Liu ; MDb ; hongchenliuu@163.com" class="auth_mail" title="E-mail the corresponding author ; Baohua Xu ; MDa ;
- 关键词：oral squamous cell carcinoma ; long non-coding RNA ; co-expression network
- 刊名：Archives of Oral Biology
- 出版年：2015
- 出版时间：October 2015
- 年：2015
- 卷：60
- 期：10
- 页码：1581-1587
- 全文大小：2610 K
文摘
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A total of 998 DEGs and 160 differentially expressed lncRNAs were screened out
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FTH1P3, PDIA3F and GTF2IRD2P1 targeted most of DEGs in co-expression network
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Up-regulated candidate targets were mainly involved in inflammation-related functions
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Up-regulated target genes were significantly enriched in Toll-like receptor pathway.