- 作者：Anita J. Fuglestad ; Ashton E. Lehmann ; Maria G. Kroupina ; Anna Petryk ; Bradley S. Miller ; S ; ra L. Iverson ; Dana E. Johnson ; Michael K. Georgieff
- 刊名：The Journal of Pediatrics
- 出版年：2008
- 出版时间：August 2008
- 年：2008
- 卷：153
- 期：2
- 页码：272-277
- 全文大小：164 K
Objective
To assess iron deficiency (ID) in international adoptees after adoption.Study design
Participants (n = 37) were adopted into the United States from Eastern Europe before they were 24 months of age. Baseline (within 1 month post-adoption) and follow-up (6 months post-adoption) assessments included routine post-adoption clinical evaluations, anthropometrics, dietary intakes, and iron measures (hemogram and serum analysis).
Results
At adoption and follow-up, mean percent transferrin saturation and mean corpucuscular volume were low compared with the US population. Mean serum ferritin concentration became lower than the US population at follow-up, although the mean daily iron intake was more than the Recommended Dietary Allowance. Participants with Giardia lamblia at baseline had more compromised iron status at baseline and follow-up. Growth rate (change in z-score/months between assessments) was negatively correlated with change in serum ferritin concentrations between baseline and follow-up (r = −0.34; P < .05).
Conclusions
International adoptees had compromised iron status, with ID more prevalent in participants with G lamblia, a parasite that may interfere with iron absorption. The persistent ID at follow-up was likely caused by the erythropoietic demands of catch-up growth.