Effect of pore size on bone ingrowth into porous titanium implants fabricated by additive manufacturing: An in vivo experiment
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- 作者：Naoya Taniguchia ; tani110@kuhp.kyoto-u.ac.jp" class="auth_mail" title="E-mail the corresponding author ; Shunsuke Fujibayashia ; shfuji@kuhp.kyoto-u.ac.jp" class="auth_mail" title="E-mail the corresponding author ; Mitsuru Takemotoa ; m.take@kuhp.kyoto-u.ac.jp" class="auth_mail" title="E-mail the corresponding author ; Kiyoyuki Sasakib ; kiy-sasaki@spcom.co.jp" class="auth_mail" title="E-mail the corresponding author ; Bungo Otsukia ; bungo@kuhp.kyoto-u.ac.jp" class="auth_mail" title="E-mail the corresponding author ; Takashi Nakamurac ; ntaka@kuhp.kyoto-u.ac.jp" class="auth_mail" title="E-mail the corresponding author ; Tomiharu Matsushitad ; matsushi@isc.chubu.ac.jp" class="auth_mail" title="E-mail the corresponding author ; Tadashi Kokubod ; kokubo@isc.chubu.ac.jp" class="auth_mail" title="E-mail the corresponding author ; Shuichi Matsudaa ; smat522@kuhp.kyoto-u.ac.jp" class="auth_mail" title="E-mail the corresponding author
- 关键词：Selective laser melting ; Porous titanium ; Additive manufacturing ; Pore size ; Bone ingrowth
- 刊名：Materials Science & Engineering C
- 出版年：2016
- 出版时间：1 February 2016
- 年：2016
- 卷：59
- 期：Complete
- 页码：690-701
- 全文大小：3257 K
文摘
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We studied the effect of pore size on bone tissue in-growth in a rabbit in vivo model.
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Titanium samples with 300/600/900 μm pore size in three-dimensionally controlled shapes were fabricated by additive manufacturing.
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Samples were well-characterized physically as well as mechanically and histologically.
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Porous implants with a pore size of 600 μm have the highest bone-material fixation ability and the best bone ingrowth.
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It is suggested that samples with a pore size of 600 μm are best suited to orthopedic applications.