A high-throughput sequence analysis of Japanese patients revealed 11 candidate genes associated with type 1 autoimmune pancreatitis susceptibility
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- 作者：Shugo Fujibayashia ; Junpei Sasajimaa ; Takuma Gotoa ; Hiroki Tanakaa ; Hidemasa Kawabatab ; Tsuneshi Fujiib ; Kazumasa Nakamurac ; Atsushi Chibac ; Nobuyuki Yanagawad ; Kentaro Moriichia ; Mikihiro Fujiyaa ; fjym@asahikawa-med.ac.jp" class="auth_mail" title="E-mail the corresponding author ; Yutaka Kohgoa
- 关键词：AIP ; autoimmune pancreatitis ; IgG4 ; immunoglobulin G fraction 4 ; HLA ; human leukocyte antigen ; HV ; healthy volunteer ; DNA ; deoxyribonucleic acid ; PCR ; polymerase chain reaction ; SNP ; single nucleotide polymorphism
- 刊名：Biochemistry and Biophysics Reports
- 出版年：2016
- 出版时间：July 2016
- 年：2016
- 卷：6
- 期：Complete
- 页码：76-81
- 全文大小：270 K
文摘
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High-throughput sequencing was performed with a custom panel of 1031 genes.
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Nine candidate genetic variants were identified in patients with type 1 AIP.
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Eight candidate genetic variants were identified in patients with relapse of AIP.
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Two candidate genes were identified in patients with extra-pancreatic lesions.