Mammalian Reverse Genetics without Crossing Reveals Nr3a as a Short-Sleeper Gene
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- 作者：Genshiro A. Sunagawa1 ; 8 ; Kenta Sumiyama2 ; 8 ; Maki Ukai-Tadenuma1 ; 8 ; Dimitri Perrin1 ; 6 ; 8 ; Hiroshi Fujishima1 ; Hideki Ukai1 ; Osamu Nishimura5 ; Shoi Shi3 ; Rei-ichiro Ohno3 ; Ryohei Narumi1 ; Yoshihiro Shimizu7 ; Daisuke Tone3 ; Koji L. Ode3 ; Shigehiro Kuraku5 ; Hiroki R. Ueda1 ; 3 ; 4 ; uedah-tky@umin.ac.jp" class="auth_mail" title="E-mail the corresponding author
- 刊名：Cell Reports
- 出版年：2016
- 出版时间：26 January 2016
- 年：2016
- 卷：14
- 期：3
- 页码：662-677
- 全文大小：4745 K
文摘
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A triple-target CRISPR method achieved almost perfect knockout efficiency
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SSS achieved non-invasive fully automated high-performance sleep phenotyping
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Genetics without crossing revealed Nr3a as a short-sleeper gene