Usefulness of a traction method using dental floss and a hemoclip for gastric endoscopic submucosal dissection: a propensity score matching analysis (with videos)

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• 作者：Sho Suzuki ; MD¹ ; Takuji Gotoda ; MD ; PhD ; FASGE¹ ; ; Yoshiyuki Kobayashi ; MD ; PhD¹ ; Shin Kono ; MD¹ ; Kunio Iwatsuka ; MD¹ ; Naoko Yagi-Kuwata ; MD¹ ; Chika Kusano ; MD ; PhD¹ ; Masakatsu Fukuzawa ; MD ; PhD² ; Fuminori Moriyasu ; MD ; PhD¹
• 关键词：DFC ; traction method using dental floss and a hemoclip ; ESD ; endoscopic submucosal dissection
• 刊名：Gastrointestinal Endoscopy
• 出版年：2016
• 出版时间：February 2016
• 年：2016
• 卷：83
• 期：2
• 页码：337-346
• 全文大小：2144 K

文摘

Although endoscopic submucosal dissection (ESD) is a significant advancement in therapeutic endoscopy, it is a complicated technique and requires considerable expertise. In this exploratory study, we evaluated the efficacy of a simple traction method that uses dental floss and a hemoclip (DFC) and was developed to overcome the technical difficulties of ESD.

Methods

In total, 238 early gastric cancers treated by ESD between May 2012 and December 2014 at Tokyo Medical University were retrospectively reviewed. Lesions treated by conventional ESD (n = 185) and by ESD with DFC (ESD-DFC) (n = 53) were compared. Multivariable analyses and propensity score matching were used to compensate for the differences in age, sex, resected specimen size, lesion location, lesion position, presence of ulceration, and operator level. The procedure time, rate of en bloc and complete resection, and rates of adverse events were evaluated between the 2 groups.

Results

Propensity score matching analysis created 43 matched pairs. Adjusted comparisons between ESD-DFC and conventional ESD showed similar treatment outcomes (en bloc resection rate: 97.7% vs 100%, P = .315; complete resection rate: 90.7% vs 95.3%, P = .397; perforation during ESD rate: 2.3% vs 2.3%, P = 1.000; post-ESD bleeding rate: 4.7% vs 4.7%, P = 1.000) but a significantly shorter procedure time for ESD-DFC (82.2 ± 79.5 minutes vs 118.2 ± 71.6 minutes, P = .002).

Conclusion

ESD-DFC facilitated rapid ESD with good visualization and traction while ensuring high curability and safety.