- 作者：Hawley E. Montgomery-Downs ; Marion E. Young ; Miriam A. Ross ; Mark J. Polak ; Susan K. Ritchie ; Susan K. Lynch
- 关键词：Sleep ; Sleep-disordered breathing ; Snoring ; Premature Infant ; Growth ; Development
- 刊名：Sleep Medicine
- 出版年：2010
- 出版时间：March 2010
- 年：2010
- 卷：11
- 期：3
- 页码：263-267
- 全文大小：190 K
BackgroundChildren who were born prematurely are at higher risk for sleep-disordered breathing (SDB) compared to their same-age peers who were born fullterm.Objective
The objective of the present study was to assess the frequency of SDB symptoms and effects on growth among preterm infants while they are still infants, with a goal of identifying risk factors to facilitate prevention and early intervention.
Methods
The Louisville pediatric SDB risk survey was administered to the primary caretakers of prematurely born infants attending the Neonatal Follow-Up Clinic at West Virginia University Children’s Hospital.
Results
Participation was 100 % among 173 consecutive patients invited to participate in the study. At 9.13 months corrected age, 8.1 % of infants born at a mean of 31.6 weeks gestation were reported to snore 3 days/week, a rate consistent with diagnosis of sleep-disordered breathing among older children. A composite of nine parent-reported symptoms was created based on factor analysis. Birth weight and size for gestational age at birth did not differ between snoring groups or correlate with the composite score. But a significant negative correlation between the composite risk for SDB score and current weight for adjusted age percentile score indicate that infants with higher SDB symptom profiles have lower weight for age (r = −.18, p = .028).
Conclusions
SDB symptoms are detectable among infants born preterm, while they are still infants. Because of their preferential risk for SDB and its somatic consequences, a primary research goal should be description of the natural history of SDB and identification of modifiable risk factors and treatment options.