Fungicides induced triazole-resistance in Aspergillus fumigatus associated with mutations of TR46/Y121F/T289A and its appearance in agricultural fields

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• 作者：Jingbei Ren ; Xiangxiang Jin ; Qian Zhang ; Yuan Zheng ; Dunli Lin ; Yunlong Yu ; ^{ylyu@zju.edu.cn}
• 关键词：Triazole ; Fungicide ; Resistance ; Aspergillus fumigatus
• 刊名：Journal of Hazardous Materials
• 出版年：2017
• 出版时间：15 March 2017
• 年：2017
• 卷：326
• 期：Complete
• 页码：54-60
• 全文大小：1293 K
• 卷排序：326

文摘

Resistance in A. fumigatus to triazole medicals was induced by triazole fungicides. Alterations in cyp51A of A. fumigatus were caused by exposure to triazole fungicides. The induced mutation TR46/Y121F/T289A was found in field strains of A. fumigatus.