Pneumocystis pneumonia associated with human immunodeficiency virus infection without elevated (1 → 3)-β-D glucan: A case report

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• 作者：Takahiro Kamada ; ^{takahiro00920619@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Kenjiro Furuta ^{k.furuta0113@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Hiromi Tomioka ^{htomy@kobe-nishishimin-hospi.jp" class="auth_mail" title="E-mail the corresponding author}
• 关键词：Acquired immunodeficiency syndrome ; Human immunodeficiency virus ; Pneumocystis pneumonia ; (1 &rarr ; 3)-β-D-glucan
• 刊名：Respiratory Medicine Case Reports
• 出版年：2016
• 出版时间：2016
• 年：2016
• 卷：18
• 期：Complete
• 页码：73-75
• 全文大小：691 K

文摘

Pneumocystis pneumonia (PCP) caused by Pneumocystis jirovecii is one of the most common opportunistic infections in immunosuppressed patients, particularly in patients with acquired immunodeficiency syndrome (AIDS). (1 → 3)-β-D-glucan is a component of the cell wall of P. jirovecii and other fungi such as Candida sp., Aspergillus sp. and Histoplasma sp. The measurement of serum (1 → 3)-β-D-glucan has been reported to be a highly sensitive test for PCP related to human immunodeficiency virus (HIV-PCP). We report a case of HIV-PCP not associated with elevated serum (1 → 3)-β-D glucan and highlight how HIV-PCP cannot be completely ruled out if (1 → 3)-β-D glucan is negative.