Intranasal Cerebrolysin Attenuates Learning and Memory Impairments in D-galactose-Induced Senescence in Mice

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• 作者：Ehsan Pourmemar ; Alireza Majdi ; Morteza Haramshahi ; Mahnaz Talebi ; Pouran Karimi ; Saeed Sadigh-Eteghad ; ^{Saeed.sadigetegad@gmail.com}
• 关键词：Intranasal ; Cerebrolysin ; Learning ; Memory ; D-galactose ; Senescence
• 刊名：Experimental Gerontology
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：87
• 期：part_PA
• 页码：16-22
• 全文大小：1120 K
• 卷排序：87

文摘

Intranasal cerebrolysin improves recognition and spatial learning and memory in d-galactose model of aging in mice. Intranasal cerebrolysin reduces d-galactose-induced increase in malondialdehyde level in the brain of mice model of ageing. Intranasal cerebrolysin reduces d-galactose-induced reduction in antioxidant enzymes activity in the brain of mice model of ageing. Intranasal cerebrolysin reduces d-galactose-induced apoptosis in the brain of mice model of ageing.