Difference in expression of matrix metalloproteinase-2 and matrix metalloproteinase-9 in patients with persistent ovarian cysts

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• 作者：Maria Rosaria Raspollini ; Francesca Castiglione ; Duccio Rossi Degl’ ; Innocenti ; Francesca Garbini ; Maria Elisabetta Coccia ; Gian Luigi Taddei
• 刊名：Fertility and Sterility
• 出版年：2005
• 出版时间：October 2005
• 年：2005
• 卷：84
• 期：4
• 页码：1049-1052
• 全文大小：105 K

文摘

Matrix metalloproteinase-1 (MMP-1), MMP-2, and MMP-9 expression with real-time quantitative polymerase chain reaction were analyzed in endometriotic and nonendometriotic ovarian cysts. Although MMP-1 was not detected, MMP-9 and MMP-2 were expressed in all of the cysts. In particular, in five of six nonendometriotic cysts (83.3 % ) MMP-2 expression was higher than in endometriotic cysts. These data may represent new molecular elements helpful in differential diagnosis of endometriotic lesions.