The sulfinyl moiety in Lewis base-promoted allylations
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- 作者：J. Robin Fulton ; Lamin M. Kamara ; Simon C. Morton ; Gareth J. Rowl ; s
- 关键词：Asymmetric catalysis ; Allylation ; Sulfoxides ; Sulfinamides ; Lewis base
- 刊名：Tetrahedron
- 出版年：2009
- 出版时间：7 November 2009
- 年：2009
- 卷：65
- 期：45
- 页码：9134-9141
- 全文大小：409 K
文摘
By employing Senanayake's oxathiazolidine-2-oxide reagent, a collection of sulfinamides was prepared and provided the first examples of sulfinamides promoting the allylation of benzaldehyde and N-benzoylhydrazones with allyltrichlorosilane. The optimum sulfinamide-derived Lewis base promoter displays comparable activity to the best sulfinyl-based Lewis bases reported. The use of bis-sulfoxides is also discussed.