SerpinI2 (pancpin) is an inhibitory serpin targeting pancreatic elastase and chymotrypsin

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• 作者：Wayne J. Higgins^a ; Gareth T. Grehan^a ; Kieran J. Wynne^b ; D. Margaret Worrall^a ; ^{mworrall@ucd.ie}
• 关键词：Pancpin ; Serpin ; Chymotrypsin ; Elastase ; Pancreatic insufficiency
• 刊名：Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：1865
• 期：2
• 页码：195-200
• 全文大小：1003 K
• 卷排序：1865

文摘

SerpinI2 cloning and recombinant protein production SerpinI2 is an inhibitory serpin that displays native instability. SerpinI2 targets pancreatic chymotrypsin and elastase. SerpinI2 can readily polymerise.