Sensorimotor gating in healthy adults tested over a 15 year period

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• 作者：Neal R. Swerdlow ; ^{nswerdlow@ucsd.edu} ; Savita G. Bhakta ; Brinda K. Rana ; Justin Kei ; Hsun-Hua Chou ; Jo A. Talledo
• 关键词：Catechol-O-methyl transferase ; Prepulse inhibition ; Sensorimotor gating ; Startle
• 刊名：Biological Psychology
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：123
• 期：Complete
• 页码：177-186
• 全文大小：1293 K
• 卷排序：123

文摘

Startle and prepulse inhibition (PPI) were tested in 487 subjects over 15 years. PPI and startle latency were stable but startle magnitude declined over 15 years. Moderating effects of specific variables on PPI largely supported published reports. PPI is reliable, and variables are known that can constrain uncontrolled variance.