Could the thromboxane A2 pathway be a therapeutic target for the treatment of obstructive sleep apnea-induced atherosclerosis?
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- 作者：Elodie Gautier-Veyreta ; b ; c ; Laetitia Van Noolena ; b ; c ; Patrick Lé ; vya ; b ; c ; Jean Louis Pepina ; b ; c ; Franç ; oise Stanke-Labesquea ; b ; c ; FStanke@chu-grenoble.fr" class="auth_mail" title="E-mail the corresponding author
- 关键词：Thromboxane A2 ; Obstructive sleep apnea ; Atherosclerosis ; Intermittent hypoxia
- 刊名：Prostaglandins and Other Lipid Mediators
- 出版年：2015
- 出版时间：September 2015
- 年：2015
- 卷：121
- 期：part_PA
- 页码：97-104
- 全文大小：839 K
文摘
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Intermittent hypoxia and obesity may activate TXA2-pathway.
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TXA2- pathway could be a link between OSA and atherosclerosis.
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Pharmacological or nutritional approaches may disrupt TXA2-pathway.
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These therapeutic strategies may treat atherosclerosis in obese OSA patients.