Biological Stress Systems, Adverse Life Events, and the Improvement of Chronic Multisite Musculoskeletal Pain Across a 6-Year Follow-Up
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- 作者：Ellen Generaal&lowast ; ; egeneraal@gmail.com ; Nicole Vogelzangs&lowast ; ; Gary J. Macfarlane&dagger ; ; Rinie Geenen&Dagger ; ; Johannes H. Smit&lowast ; ; Eco J.C.N. de Geus§ ; ; Joost Dekker&lowast ; ; ¶ ; ; Brenda W.J.H. Penninx&lowast ;
- 关键词：Chronic pain ; cortisol ; inflammation ; autonomic nervous system ; life change events
- 刊名：The Journal of Pain
- 出版年：2017
- 出版时间：February 2017
- 年：2017
- 卷：18
- 期：2
- 页码：155-165
- 全文大小：429 K
- 卷排序：18
文摘
Biological and psychosocial stress are known to be correlated with chronic pain. The prospective association of both stress types with improvement of pain is unclear. Neither biological stress systems nor life events predicted improvement of pain. Biological changes may rather be consequences of chronic pain itself.