Effects of magnetization transfer on T1 contrast in human brain white matter
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- 作者：Peter van Gelderen ; Xu Jiang ; Jeff H. Duyn ; jhd@helix.nih.gov" class="auth_mail" title="E-mail the corresponding author
- 关键词：Brain tissue ; White matter ; Myelin ; T1 contrast ; Magnetization transfer ; Macromolecular content
- 刊名：NeuroImage
- 出版年：2016
- 出版时间：March 2016
- 年：2016
- 卷：128
- 期：Complete
- 页码：85-95
- 全文大小：1350 K
文摘
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MRI T1 contrast to study brain anatomy depends on experimental details.
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Variability is introduced by the type of RF inversion pulse used.
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It can be attributed to the magnetization level of macromolecular protons.
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It can be minimized by using long inversion times and high RF power.
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Proper modeling of this effect allows quantification of tissue parameters.