Thalamocortical relationship in epileptic patients with generalized spike and wave discharges — A multimodal neuroimaging study
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- 作者：Clara Huishi Zhanga ; Zhiyi Shab ; John Mundahla ; Sa Liua ; c ; Yunfeng Lua ; Thomas R. Henryb ; Bin Hea ; d ; binhe@umn.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：Idiopathic generalized epilepsy ; Generalized spike-wave discharge ; EEG ; fMRI ; Independent component analysis ; Granger Causality ; Functional connectivity ; Directed transfer function (DTF) ; Adaptive directed transfer function (ADTF)
- 刊名：NeuroImage: Clinical
- 出版年：2015
- 出版时间：2015
- 年：2015
- 卷：9
- 期：Complete
- 页码：117-127
- 全文大小：1464 K
文摘
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We studied the generalized epilepsy mechanisms and networks using EEG and fMRI.
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Connectivity analysis revealed mediodorsal nucleus–medial frontal cortex network.
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We investigated the thalamocortical network using Granger Causality.
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Thalamus was found to be the prominent player in the thalamocortical interaction.