Computational models of epileptiform activity
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- 作者：Fabrice Wendlinga ; b ; fabrice.wendling@univ-rennes1.fr" class="auth_mail" title="E-mail the corresponding author ; Pascal Benqueta ; b ; Fabrice Bartolomeic ; d ; Viktor Jirsac ; d
- 关键词：Epilepsy ; Epileptiform activity ; Computational model ; Neural mass ; Neural field ; Detailed network ; Formal mathematical model ; Interictal epileptic spike ; High-frequency oscillations ; Fast onset ; Seizure initiation ; Seizure propagation ; Spike-wave discharge ; Status epilepticus
- 刊名：Journal of Neuroscience Methods
- 出版年：2016
- 出版时间：15 February 2016
- 年：2016
- 卷：260
- 期：Complete
- 页码：233-251
- 全文大小：4578 K
文摘
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Neural mass, neural field, detailed network and formal models are reviewed.
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These models are aimed at reproducing and explaining epileptic activity.
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Biology-inspired and mathematical models have advantages and limitations.
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Detailed network models are required to simulate some particular HFOs.
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Neural mass/field models provided insights in partial and generalized epilepsies.