Updating the African human mitochondrial DNA tree: Relevance to forensic and population genetics

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• 作者：Tanja Heinz^a ; ¹ ; Maria Pala^b ; Alberto Gó ; mez-Carballa^a ; Martin B. Richards^b ; Antonio Salas^a ; ¹ ; ^{antonio.salas@usc.es}
• 关键词：PhyloTree ; Haplogrep ; EMPOP ; Mitochondrial DNA ; Africa ; America ; Ancestry
• 刊名：Forensic Science International: Genetics
• 出版年：2017
• 出版时间：March 2017
• 年：2017
• 卷：27
• 期：Complete
• 页码：156-159
• 全文大小：267 K
• 卷排序：27

文摘

The mtDNA phylogeny is commonly used in many forensic and biomedical applications. >2200 mitogenomes of recent African ancestry, namely, belonging to L(×M,N) haplogroups, were analyzed with the aim of improving the known worldwide phylogeny. We built maximum-parsimony phylogenetic trees and more than 300 new minor sub-clades were identified. Time to the Most Recent Common Ancestor (TMRCA) was computed for each node of the phylogeny using maximum-likelihood procedures. We comment on the relevance of phylogeography of African trees in forensic genetics, but also in anthropological studies, such as those related to the transatlantic slave trade.