Heterogeneous genomic locations within NS3, NS4A and NS4B identified for genotyping and subtyping of Hepatitis C virus: A simple genome analysis approach
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- 作者：Sajid Mansoora ; b ; Aneela Javeda ; javedaneela@googlemail.com" class="auth_mail" title="E-mail the corresponding author ; Amjad Alia ; Atika Mansoorb
- 关键词：bs ; bootstrap ; GTR ; general time reversible ; HCV ; Hepatitis C virus ; MCL ; maximum composite likelihood ; ML ; maximum likelihood ; N-J ; neighbor-joining ; RA ; reference alignment ; SVR ; sustained virological response
- 刊名：Infection, Genetics and Evolution
- 出版年：2016
- 出版时间：October 2016
- 年：2016
- 卷：44
- 期：Complete
- 页码：61-68
- 全文大小：1051 K
文摘
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Simple genome analysis strategy employed to identify genomic regions for genotyping
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Identified regions to depict genomic diversity as depicted by the whole genome
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Exact genomic locations wrt H77 found out for core-E1, NS5B & NS3
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NS3 identified as a new potential alternate for genotyping/subtyping
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This simple manual strategy can also be used for other small genome pathogens