Single centre experience: Long term outcomes in spina bifida patients

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• 作者：Georgina Malakounides ; Frank Lee ; Feilim Murphy ; Su-Anna Boddy
• 关键词：Spina bifida ; Neuropathic ; Renal failure ; Mortality
• 刊名：Journal of Pediatric Urology
• 出版年：2013
• 出版时间：October, 2013
• 年：2013
• 卷：9
• 期：5
• 页码：585-589
• 全文大小：221 K

文摘

Objective

To determine our single centre experience of long term renal function and mortality rates of our cohort of spina bifida patients born since 1970.

Materials and methods

We collected a prospective database and included all patients born with spina bifida between 1970 and 2011 managed by our centre. Data we collected included the glomerular filtration rates, results of renal tract imaging, management strategies and mortalities.

Results

Of 160 patients identified, 120 were included for analysis with a mean age of 20 years. In our cohort 48 % (58/120) had normal renal function and only 1.6 % (2/120) had severe renal impairment or end stage renal failure. There was a mortality rate of 4.4 % and there were no deaths from renal failure.

Conclusion

Spina bifida patients have been reported to have high mortality rates and high morbidity secondary to renal failure. Historical data does not appear to reflect current advancements and we would therefore be more optimistic when counselling families about long term survival into adulthood.