Alcohol withdrawal in epileptic rats — Effects on postictal depression, respiration, and death
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- 作者：Srinivasa P. Kommajosyula ; Marcus E. Randall ; Srinivasan Tupal ; Carl L. Faingold ; cfaingold@siumed.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：%SpO2 ; percent oxygen saturation ; AGSz ; audiogenic seizures ; ETX ; ethanol withdrawal ; GEPR-9 ; genetically epilepsy-prone rat ; PID ; postictal depression ; PTC ; post-tonic generalized clonus ; RD ; respiratory distress ; SD ; spreading depression ; SUDEP ; sudden unexpected death in epilepsy
- 刊名：Epilepsy & Behavior
- 出版年：2016
- 出版时间：November 2016
- 年：2016
- 卷：64
- 期：part_PA
- 页码：9-14
- 全文大小：481 K
文摘
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Alcohol withdrawal increased the duration of postictal depression in epileptic rats.
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Postseizure respiratory distress increased in epileptic rats in alcohol withdrawal.
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Alcohol withdrawal increases seizure-induced mortality in epileptic rats.
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This mortality increase confirms the risk of alcohol seen in human SUDEP.