Design of binary polymeric platforms containing ɩ-carrageenan and hydroxypropylcellulose for use in cataract surgery
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- 作者：David S. Jones ; d.jones@qub.ac.uk" class="auth_mail" title="E-mail the corresponding author ; Gerard P. Rafferty ; Gavin P. Andrews
- 关键词：Ophthalmic viscoelastic devices ; ɩ-Carrageenan ; Hydroxypropylcellulose ; Viscoelastic ; Adhesiveness ; Interaction parameter
- 刊名：Carbohydrate Polymers
- 出版年：2016
- 出版时间：10 December 2016
- 年：2016
- 卷：154
- 期：Complete
- 页码：296-304
- 全文大小：789 K
文摘
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Ophthalmic viscoelastic devices (OVDs) were designed composed of HPC and ɩ-carrageenan (Carr).
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The rheological and compressional properties of the polymer blends were characterised.
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HPC and Carr were shown to physically interact in both dilute and gel states.
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Binary platforms offered a wide range of rheological and compressional properties.
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Platforms containing 3% HPC and 1% or 2% Carr exhibited properties advantageous for use as OVDs.